dianabol steroids

The bioavailability after ingestion of standard. The maximum plasma concentration dianabol steroids is reached after 2 h. After ingestion. Almost does not bind to plasma proteins. It accumulates in the salivary glands, muscles, liver and kidneys. Provided unchanged by the kidneys. When renal function is possible accumulation of the drug.

Contraindications

  • dianabol steroids priceHypersensitivity to the drug;
  • diabetic ketoacidosis, diabetic precoma, coma;
  • pronounced renal dysfunction;
  • cardiac and respiratory failure, acute phase of myocardial infarction, acute cerebrovascular accident, dehydration, chronic alcoholism, and other conditions that may contribute to the development of lactic acidosis;
  • lactic acidosis and instructions to him in history;
  • Pregnancy and breast-feeding;
  • major surgery or injury, when shown holding insulin;
  • liver dysfunction, acute alcohol poisoning;
  • use for at least 2 days prior to and within 2 days after the radioisotope or radiological examinations with iodide introduction. contrast agent;
  • compliance with a hypocaloric diet (less than 1000 calories / day).

Do not use the drug in patients older than 60 years, performing heavy physical work, which is associated with an increased risk of developing lactic acidosis.

Dosing and Administration
Dose Metfogamma ® 500 is determined individually, taking into account the level of glucose in the blood. The initial dose is typically 500-1000 mg (1-2 tablets) per day may further gradual increase in the dose depending on the effect of therapy.
Supportive daily dose of 1000-2000 mg (2-4 tablets) per day.
The maximum daily dose – 3 g (6 tablets) appointment of higher doses does not contribute to the effect of the treatment.
Dianabol steroids should be taken with food, the whole with a little liquid (a glass of water).
The course of drug treatment is long.
As a result of high-risk development of lactic acidosis, the dose should be reduced in severe metabolic disorders.

Side effect On the part of the gastrointestinal tract : nausea, vomiting, abdominal pain, diarrhea, lack of appetite, “metallic” taste in the mouth. In these cases, usually not required discontinuation of treatment and symptoms are independently without changing dose. The frequency and severity of side effects from the gastrointestinal tract may be reduced by gradually increasing the dose of metformin. In rare cases – abnormalities liver function tests or hepatitis, transient after discontinuation of the drug. Allergic reactions :. Rash From the Endocrine : hypoglycemia (especially when used in inadequate doses).On the part of metabolism : rarely – lactic acidosis (requires termination treatment), long-term treatment – vitamin deficiencies Bi2 (malabsorption). From the hematopoietic system : in some cases – megaloblastic anemia.

 

Overdose
If overdose may develop lactic acidosis fatal. The reason for the development of lactic acidosis may also be the accumulation of the drug due to renal dysfunction. Early symptoms of lactic acidosis include nausea, vomiting, diarrhea, drop in body temperature, abdominal pain, pain in the muscles, in the future may be marked shortness of breath, dizziness, impaired consciousness and coma development. In case of lactic acidosis symptoms, drug treatment dianabol steroids you need to stop immediately, the patient hospitalized immediately and determine the concentration of lactate, to confirm the diagnosis. The most effective measure for the excretion of lactate and metformin is hemodialysis. Spend as symptomatic treatment. In combination therapy with a sulfonylurea may develop hypoglycaemia.

Interaction with other medicinal products
In an application with sulfonylureas, acarbose, insulin, nonsteroidal anti-inflammatory agents, monoamine oxidase inhibitors, oxytetracycline, angiotensin converting enzyme inhibitors, clofibrate derivatives, cyclophosphamide, ß-blockers may increase the hypoglycemic effect of metformin. While the use of corticosteroids, oral contraceptives, epinephrine, sympathomimetics, glucagon, thyroid hormones, thiazide and “loop” dianabol pills diuretics, phenothiazine derivatives, derivatives of nicotinic acid may reduce the hypoglycemic action of metformin.
Cimetidine slows the elimination of metformin, thus increasing the risk of lactic acidosis.
Metformin may weaken the effect of indirect anticoagulants (coumarin derivatives). At simultaneous reception of alcohol may develop lactic acidosis.
Nifedipine increases absorption, slows down.
Incompatible with ethanol (lactic acidosis).
Cationic drugs (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, vancomycin), secreted in tubule, competing for kanaltsievye transport systems and long-term therapy may increase.

Cautions
During treatment necessary to monitor renal function. At least 2 times a year, as well as the appearance of myalgia should be determination of lactate in plasma. Possible use of the in combination with sulfonylureas or insulin. In this case, you need a particularly careful control of blood glucose levels.

Effects on ability to drive vehicles and operate machinery
Using the drug in monotherapy does not affect the ability to drive vehicles and operate machinery.
With the combination of metformin with other hypoglycemic agents (sulfonylureas, insulin, etc.) may develop hypoglycemic conditions under which deteriorating ability to road management and occupation of other potentially hazardous activities that require increased attention and rapid psychomotor reactions. where can i get anabolic steroids winstrol capsules how to buy steroid mexican testosterone cypionate mexican pharmacy steroids buy mexican anabolic steroids from mexico

dianabol side effects for men

Following oral administration, metformin is absorbed from the gastrointestinal tract. The bioavailability after ingestion of standard. The maximum plasma concentration is reached after 2 h. After ingestion. Almost does not bind to plasma proteins. It accumulates in the salivary glands, muscles, liver and kidneys. Provided unchanged by the kidneys. When renal function is dianabol side effects for men possible accumulation of the drug.

Indications Diabetes mellitus type 2, with no tendency to ketoacidosis (especially in patients who are obese) when poor diet.

Contraindications

  • Hypersensitivity to the drug;
  • diabetic ketoacidosis, diabetic precoma, coma;
  • pronounced renal dysfunction;
  • cardiac and respiratory failure, acute phase of myocardial infarction, acute cerebrovascular accident, dehydration, chronic alcoholism, and other conditions that may contribute to the development of lactic acidosis;
  • lactic acidosis and instructions to him in history;
  • Pregnancy and breast-feeding;
  • major surgery or injury, when shown holding insulin;
  • liver dysfunction, acute alcohol poisoning;
  • use for at least 2 days prior to and within 2 days after the radioisotope or radiological examinations with iodide introduction. contrast agent;
  • compliance with a hypocaloric diet (less than 1000 calories / day).

Do not use the drug in patients older than 60 years, performing heavy physical work, which is associated with an increased risk of developing lactic acidosis.

Dosing and Administration Determined individually, taking into account the level of glucose in the blood. The initial dose is typically 500-1000 mg (1-2 tablets) per day may further gradual increase in the dose depending on the effect of therapy. Supportive daily dose of 1000-2000 mg (2-4 tablets) per day. The maximum daily dose – 3 g (6 tablets) appointment bradley martin steroids of higher doses does not contribute to the effect of the treatment dianabol side effects for men.

The course of drug treatment is long. As a result of high-risk development of lactic acidosis, the dose should be reduced in severe metabolic disorders.

Side effect On the part of the gastrointestinal tract : nausea, vomiting, abdominal pain, diarrhea, lack of appetite, “metallic” taste in the mouth. In these cases, usually not required discontinuation of treatment and symptoms are independently without changing dose. The frequency and severity of side effects from the gastrointestinal tract may be reduced by gradually increasing the dose of metformin. In rare cases – abnormalities liver function tests or hepatitis, transient after discontinuation of the drug. Allergic reactions :. Rash dianabol side effects for men From the Endocrine : hypoglycemia (especially when used in inadequate doses).On the part of metabolism : rarely – lactic acidosis (requires termination treatment), long-term treatment – vitamin deficiencies Bi2 (malabsorption). From the hematopoietic system : in some cases – megaloblastic anemia.

Overdose If overdose may develop lactic acidosis fatal. The reason for the development of lactic acidosis may also be the accumulation of the drug due to renal dysfunction dianabol review. Early symptoms of lactic acidosis include nausea, vomiting, diarrhea, drop in body temperature, abdominal pain, pain in the muscles, in the future may be marked shortness of breath, dizziness, impaired consciousness and coma development. In case of lactic acidosis symptoms, drug treatment you need to stop immediately, the patient hospitalized immediately and determine the concentration of lactate, to confirm the diagnosis. The most effective measure for the excretion of lactate and metformin is hemodialysis. Spend as symptomatic treatment. In combination therapy dbol with with a sulfonylurea may develop hypoglycaemia.

dianabol side effects for men onlineInteraction with other medicinal products In an application with sulfonylureas, acarbose, insulin, nonsteroidal anti-inflammatory agents, monoamine oxidase inhibitors, oxytetracycline, angiotensin converting enzyme inhibitors, clofibrate derivatives, cyclophosphamide, ß-blockers may increase the hypoglycemic effect of metformin. While the use of corticosteroids, oral contraceptives, epinephrine, sympathomimetics, glucagon, thyroid hormones, thiazide and “loop” diuretics, phenothiazine derivatives, derivatives of nicotinic acid may reduce the hypoglycemic action of metformin. Cimetidine slows the elimination of metformin, thus increasing the risk of lactic acidosis. Metformin may weaken the effect of indirect anticoagulants (coumarin derivatives). At simultaneous reception of alcohol may develop lactic acidosis. Nifedipine increases absorption,dianabol side effects for men , slows down. Incompatible with ethanol (lactic acidosis). Cationic drugs (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, vancomycin), secreted in tubule, competing for kanaltsievye transport systems and long-term therapy may increase.

Cautions During treatment necessary dianabol side effects to monitor renal function. At least 2 times a year, as well as the appearance of myalgia should be determination of lactate in plasma. Possible use of the drug Metfogamma ® 850 in combination with sulfonylureas or insulin. In this case, you need a particularly careful control of blood glucose levels.

Effects on ability to drive vehicles and operate machinery Using the drug in monotherapy does not affect the ability to drive vehicles and operate machinery. With the combination of metformin with other hypoglycemic agents (sulfonylureas, insulin, etc.) may develop hypoglycemic conditions under which deteriorating ability to road management and occupation of other potentially hazardous activities that require increased attention and rapid psychomotor reactions.

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Collagen accelerates the growth, maturation and structuring of granulation tissue, promotes epithelialization. It reduces the risk of the formation of hypertrophic scars. When applied to a wound sponge tightly to the surface, it absorbs wound discharge, swelling and gradually lysed, releasing its constituent dianabol review. Collagen exposed in the wound gradual biodegradation. Lysis and resorption
Sponge prevents loss of fluid from the wound surface, preventing it from drying out and protects the wound from external influences and infections.

Indications
trophic ulcers, pressure ulcers, deep and long-term non-healing wounds, superficial burns to the skin.

Contraindications: Hypersensitivity. The presence of excess granulation in the wound.

Dosage and administration:
dianabol review bodybuildingOutwardly. The wound must be treated beforehand with an antiseptic solution and remove the remnants of necrotic tissue. In the presence of purulent discharge medication is recommended to combine with antiseptic solutions such as gidroksimetilhinoksalindioksida (dioxidine), wetting them sponge. The sponge is removed from the packaging immediately before use aseptically. The number and size of the sponge is selected in accordance with the area and depth of the wound. If necessary, the sponge is cut into pieces of desired size and shape. Sponge should fit snugly to the entire surface of the wound and its edges extend beyond the 1-1.5 cm. When the sponge need to close the fixing bandage or two layers of cheesecloth. Frequency of dressing depends on the depth and area of the wound surface, exudate intensity and availability of necrotic masses. Status monitor 1 wound once a day with a slight amount of discharge, and 2 times a day with abundant. The sponge is completely impregnated wound discharge are removed and replaced with a new one. If the sponge in the wound dry and bandaged recommended 1 times in 2 – 3 days, during this time the sponge lysed. If the sponge is not resolved, and there is no indication for ligation (pain, burning sensation in the wound, accumulation of purulent exudate, presence of allergic reactions), it is not removed, dianabol side effects for men. The course of treatment is carried out until complete epithelialization, and dianabol review wound granulation tissue filling the entire depth.

Side effects:
Allergic reactions such as itching, redness, burning short. Pain in the wound area (due to its contraction when dry sponge).

The interaction with other drugs
product is compatible with external applications of antibacterial, antiseptic and the anesthetic drugs.

Special instructions
for removing the pain of the wounds contraction sponge needed, without having to remove the sponge, dampen it with 0.25% solution of procaine, or an aqueous solution of 0.02% nitrofural. Product form.Sponge sizes (50 ± 5) x (50 ± 5) mm 1 pc. and (90 ± 10) x (90 ± 10) mm 1 pc. packed tightly in a two-layer package made of polyethylene film, or in a container of a film of PVC and aluminum foil with a heat seal coating, or flexible container of the film “Poliform” and laminated paper, or only from the film “Poliform”.
The two-layer packet or container, together with instructions on the application is placed dianabol review in a cardboard box. alpha pharma usa female bodybuilder youtube adidas power perfect 2 epic bodybuilding motivation health effects of steroids massularia acuminata steroid street names

dianabol results

The mechanism of action consists in biochemical restoration of 5-nitro intracellular transport proteins of anaerobic microorganisms and protozoa. The recovered 5-nitro interacts with DNA microbial cells by inhibiting the synthesis of nucleic acids, which leads to the death of the bacteria. Dianabol results active against:

  • simple: of Trichomonas vaginalis, of Entamoeba histolytica, of Giardia intestinalis, Lamblia spp,.
  • anaerobic bacteria: of Bacteroides spp. (including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus , Bacteroides thetaiotaomicron, Bacteroides vulgatus), Clostridium spp, Eubacterium spp, Fusobacterhtm spp, Peptococcus spp, Peptostreptococcus spp), Prevotella….. spp. (incl.. Prevotella bivia, Prevotella buccae, Prevotella disiens), Veillonella spp. ;
  • facultative anaerobes: of Gardnerella vaginalis, Helicobacterpylori, of Campylobacter spp, including jejuni of Campylobacter. .

dianabol results after 2 weeksThe range of the minimum inhibitory concentrations for these strains is 0,125-6,25 mg / ml.
Metronidazole in combination with amoxicillin is active against Helicobacter pylori (amoxicillin suppresses the development of metronidazole resistance).
To metronidazole insensitive aerobic microorganisms and facultative anaerobes, but in the presence of a mixed flora (aerobes and anaerobes) metronidazole acts synergistically with antibiotics effective against usual aerobes.
Increases the sensitivity of tumors to radiation, causes sensitization on alcohol (disulfiramopodobnyh action), stimulates reparative processes.
When administered intravenously, 500 mg for 20 min, the maximum serum concentration achieved after 1 hour and 35.2 g / ml; after 4 h and 8 h the concentration of 33.9 mg / ml and 25.7 mcg / ml, respectively. Typically, a therapeutic blood serum concentration is maintained for 6-8 hours. In normal bile concentration of metronidazole in bile after intravenous administration can significantly exceed the concentration in the plasma.
It has a high penetrating power, achieving bactericidal concentrations in most tissues and body fluids, including light, kidney, liver, skin, spinal fluid, brain, bile, saliva, amniotic fluid, abscess cavity, vaginal secretions, semen, breast milk, penetrates the blood-brain barrier (BBB) and the placental barrier. The volume of distribution: adults – about 0.55 l / kg, newborns 0.54-0.8) l / kg. Communication with the plasma protein-10-20%.
In the body, is metabolized about 30-60% metronidazole by hydroxylation, oxidation and glyukuronirovaniya. The major metabolite of (2-oximetronidazole) protivoprotozoynoe and also provides antimicrobial effect.
The half-life (T ½ ) with normal hepatic function – 8 hours (6 to 12 hours) in alcoholic liver injury -18 hours (10 to 29 hours). In infants born at 28-30 weeks’ gestation, the T ½ of about 75 hours, at 32-35 weeks of gestation – 35 hours and at 36-40 weeks of pregnancy -. 25 hours
excreted by the kidneys – 60-80% (20% unaltered) through the gut and – 6-15%.
Renal clearance – 10.2 ml / min. In patients with impaired renal function after re-introduction can be observed cumulation of metronidazole in blood serum (therefore in patients with severe renal insufficiency should reduce the frequency of administration).
Metronidazole and main metabolites are quickly removed from the blood by hemodialysis (elimination half-life is reduced to 2.6 hours). When peritoneal dialysis is displayed in small quantities.

Indications

  • infections caused by Bacteroides spp. (including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus ) – bone and joint infections, central nervous system infections, including meningitis, brain abscess, bacterial endocarditis and pneumonia, empyema and lung abscess;
  • infections caused by species of Bacteroides, including a group of Bacteroides fragilis , as well as the types of Clostridium, Eubacterium, Peptococcus and Peptostreptococcus – abdominal infections (peritonitis, intra-abdominal abscess, liver abscess), pelvic infections (endometritis, endomyometritis, abscess of the fallopian tubes and ovaries, infections vaginal fornix after surgical operations, pelvic abscess), skin and soft tissue infections (including post-surgical wounds);
  • sepsis / bacteremia caused by species of Bacteroides , including a group of Bacteroides fragilis and Clostridium spp.
  • prevention of postoperative infectious dianabol results complications (especially for interventions on the colon, rectum, okolorektalnoy area, during gynecological operations and abdominal organs, with appendectomy), carried out before surgery, intraoperatively and postoperatively;
  • protozoal infections: extra-intestinal amebiasis (including amebic liver abscess), intestinal amebiasis (amebic dysentery), trichomoniasis, Trichomonas vaginitis, urethritis Trichomonas, Giardia (giardiasis), balantidiasis, cutaneous leishmaniasis;
  • Radiotherapy patients with tumors – as radiosensitizing agents in cases where the resistance is caused by hypoxia in the tumor cells of the tumor.

Contraindications:
Hypersensitivity to metronidazole or other 5-nitroimidazole derivatives, leukopenia (including in the anamnesis), organic lesions of the central nervous system (in Vol. H. Epilepsy), hepatic failure (in the case of the appointment of large doses), pregnancy (I term ), lactation.

Precautions
Pregnancy (II-III trimesters), renal / hepatic failure.

Dosage and administration
intravenously to adults and children over 12 years: an initial dose of 0.5-1 g (the duration of infusion – 30-60 minutes), and then every 8 hours to 0.5 g at a rate of 5 ml / min. Treatments – 7 days, but intravenous injection is continued for a longer time if necessary. The maximum daily dose – 4 g make the transition to support the ingestion of a dose of 0.4-0.5 g 3-4 times / day with improvement of the patient’s condition may be needed.
Children under 12 years: metronidazole administered in the same way in a single . 7.5 mg / kg (30-40 minutes) every 8 hours
When septic diseases usually spend 1 course of treatment.
For the prevention of postoperative infectious complications – adults and children over 12 years prescribed intravenously at a dose of 15 mg / kg ( about 1 g to 70 kg patient) of body weight for 1 hour before the surgery (the duration of infusion – 30-60 min), then repeated intravenous drip metronidazole at a dose of 7.5 mg / kg (about 0.5 g of patient body weight 70 kg) every 6 hours after the first administration.After 1 -2 days after the operation (when it is allowed ingestion) – to pass into the reception metronidazole at a dose of 7.5 mg / kg (about 0.5 g to 70 Kg patient body weight) every 6-8 hours for 7 days dianabol results.
Patients with chronic renal failure with creatinine clearance less than 30 ml / min and / or hepatic insufficiency, the maximum daily dose – not more than 1 g, the multiplicity of application -. 2 times a day
as a radio-drug is administered in / in the drip rate of 160 mg / kg or 6.4 g / m body surface for 0.5-1.0 hours prior to irradiation. Apply before each exposure within 1-2 weeks. The remainder of the radiation therapy Metronidal not apply. The maximum single dose should not exceed 10 g, course – ’60 to remove the intoxication caused by irradiation, used drip of 5% dextrose solution, gemodeza or 0.9% sodium chloride solution.
In cervical cancer, skin cancer, is used as a local applications (3 g was dissolved in 10% dimethyl sulfoxide solution) moistened tampons, which are used topically for 1.5 – 2 hours prior to irradiation). In case of bad application of the regression of the tumor was carried out for the entire course of radiation therapy. If the positive dynamics of the purification of tumor necrosis – within the first 2 weeks of treatment.

Side effect From the digestive system : diarrhea, anorexia, nausea, vomiting, intestinal colic, constipation, “metallic” taste in the mouth, dry mouth, glossitis, stomatitis, pancreatitis. From the nervous system : dizziness, incoordination, ataxia, confusion, irritability, depression, irritability, fatigue, insomnia, headache, seizures, hallucinations, peripheral neuropathy. Allergic reactions : urticaria, skin rash, redness of the skin, nasal congestion, fever, arthralgia. From the mochevydelitelnoy system : dysuria, cystitis , polyuria, urinary incontinence, candidiasis, urine staining in red-brown color. Local reactions : thrombophlebitis (pain, redness or swelling at the injection site). Other : neutropenia, leukopenia, flattening of the T wave on the ECG.

Cautions
During treatment of ethanol is contraindicated reception (development disulfiramonodobnoy reaction: abdominal cramping, nausea, vomiting, headache, sudden rush of blood to the face) dianabol results.
. In the long-term treatment is necessary to control blood picture
At leucopenia the possibility of further treatment depends on the risk infectious process.
The appearance of ataxia, dizziness and any other worsening of neurological status of patients required discontinuation of treatment.
It may immobilize treponema and lead to a false positive test Nelson.
urine stains in dark color.
in the period of lactation should stop breastfeeding.

Overdose
No specific overdose symptoms are not present.
Treatment – specific antidote is not known. Therapy of overdose is hemodilution, supportive and symptomatic therapy. In severe cases, hemodialysis is used.

Interaction with other drugs
Metronidal ® is not recommended to be mixed with other drugs or be used as a solvent.
Enhances the effects of indirect anticoagulants, which leads to increased formation of prothrombin time.
Similarly, disulfiram causes intolerance of ethanol. The simultaneous use of disulfiram can lead to a variety of neurological symptoms (interval between administration – at least 2 weeks).
Cimetidine inhibits metronidazole metabolism, which may lead to an increase in its concentration in the serum and an increased risk of side effects.
Co-administration of drugs that stimulate enzymes microsomal oxidation in the liver (phenobarbital, phenytoin), may accelerate the elimination of metronidazole, resulting in reduced plasma concentration.
When concomitantly with dianabol results drugs lithium may increase the concentration of the latter in the plasma and the development of symptoms of intoxication.
it is not recommended to combine with non-depolarizing muscle relaxants (vecuronium bromide ).
Sulfonamide enhance the antimicrobial action of metronidazole. anti estrogens & fat loss

dianabol

Dianabol is an antiprotozoal and antibacterial broad spectrum of action. Not sensitive to metronidazole aerobic microorganisms and facultative anaerobes, but in the presence of mixed flora (aerobes and anaerobes) metronidazole acts synergistically with antibiotics effective against conventional aerobes.
The drug has a high penetrating power, achieving bactericidal concentrations in most tissues and body fluids, including the lungs, kidneys, liver, skin, spinal fluid, brain, bile, saliva, amniotic fluid, oral abscesses, vaginal secretions, semen, breast milk . Binding to blood proteins weak and does not exceed 10-20%. In normal bile concentration of metronidazole in bile after intravenous administration can significantly exceed the concentration in the blood plasma metronidazole dianabol results.

In patients with impaired renal function after repeated administration of the drug can be observed accumulation of metronidazole in blood serum. Therefore, in patients with severe renal insufficiency receiving frequency of metronidazole should be reduced.

Indications
Metronidazole Injection is recommended for the treatment of infections caused by susceptible to malaria infections:

 

  • prevention and treatment of anaerobic infections in surgical interventions, mainly in the abdominal cavity and mochevshodyaschih ways;
  • Combination therapy of severe mixed aerobic-anaerobic infections;
  • severe intestinal and hepatic amoebiasis;
  • sepsis;
  • peritonitis;
  • osteomyelitis;
  • gynecological infections;
  • pelvic abscesses and brain;
  • abscessed pneumonia;
  • gas gangrene;
  • infections of skin and soft tissues, bones and joints.Contraindications
  • hypersensitivity to metronidazole or other nitroimidazole derivatives;
  • organic CNS;
  • blood diseases;
  • 1 trimester of pregnancy;
  • II and III trimesters of pregnancy – only for health reasons;
  • nursing mothers – by prescription, while the termination of breastfeeding.Dosing and Administration
    Intravenous Metronidazole is indicated in severe infections, as well as the absence of the possibility of ingestion of the drug.For adults and children over 12 years of single dose of 500 mg, the rate of intravenous continuous (jet) or drip – 5 ml per minute. The interval between injections – 8 hours. Duration of treatment is determined individually. The maximum daily dose – not more than 4 g As indicated, depending on the nature of infection, making the transition to maintenance therapy with oral metronidazole forms.Children under the age of 12 Metronidazole is administered 7.5 mg / kg of body weight in 3 divided doses at a rate of 5 ml per minute.
    For the prevention of anaerobic infections before elective surgery on the pelvic organs and the urinary tract in adults and children over 12 years Metronidazole is administered in the form of infusions at a dose of 500-1000 mg, per day of surgery and on the following day -to dose of 1500 mg / day (500 mg every 8 hours).Dianabol intravenous infusion is not recommended to mix with other drugs!Interaction with other drugs
    When using Metronidazole Injection interaction with other drugs slightly, but caution should be exercised with concomitant administration of some drugs:dianabol (methandrostenolone)Warfarin and other indirect anticoagulants. Metronidazole increases the effects of anticoagulants, which leads to increased formation of prothrombin time. Disulfiram (esperal). Concomitant use may lead to the development of a variety of neurological symptoms, therefore should not be administered Metronidazole patients who have taken disulfiram within the last two weeks . cimetidine inhibits metabolism metronidazole, which may lead to an increase in its concentration in the serum and an increased risk of side effects. Co-administration of drugs that stimulate enzymes microsomal oxidation in liver(phenobarbital, phenytoin) may accelerate the elimination of metronidazole, resulting in lowered concentration in plasma. Patients receiving long-term treatment with drugs lithium at high doses when taking Metronidazole may increase the concentration of lithium in the blood plasma, and development of intoxication symptoms. The antimicrobial activity of metronidazole is enhanced in combination with sulphonamides and antibiotics.Side effects: the part of the gastrointestinal tract: nausea, vomiting, diarrhea, lack of appetite, unpleasant metallic taste in the mouth, epigastric pain, the part of the central nervous system: long-term use – headache, dizziness, irritability, depression, dianabol insomnia. weakness; in some cases – confusion, hallucinations, convulsions; With the genitourinary system: a burning sensation in the urethra, excessive development of fungal vaginal flora (candidiasis) Dermatological reactions: allergic reactions (skin rash, pruritus, urticaria), the part of the musculoskeletal arthralgia apparatus; From the hematopoietic system: . leukopenia while receiving metronidazole may experience a red-brown staining of urine.

 

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