Pharmachologic effect
Menotropin is a combination of hormones in the anterior lobe of the pituitary gland. This substance is produced from donor raw materials (urine of women in the menopausal period). The drug has a strong gonadotropic effect, which leads to stimulation of the processes of producing sex hormones.
The effect of the drug depends on the sex of the patient. When using the drug in women, the estrogen content rises, which stimulates the maturation of follicles in the ovaries. In addition, characteristic changes occur in the inner lining of the uterus (endometrium) – increasing the thickness of the mucosa (proliferation), which facilitates the introduction of a fertilized egg.
In the body of male patients, there is also an increase in the content of the sex hormone – testosterone, which mainly stimulates the formation of spermatozoa, leads to an increase in their mobility, and so on. In other words, the quality of sperm is normalized.
Side effects
The introduction of HuMoG solutions may lead to the following side effects: bloating, pain in the mammary glands, vomiting, gynecomastia (growth of mammary glands in men), changes in laboratory blood and urine indicators, fluid accumulation in the abdominal and thoracic cavities, increased body temperature, pain in the Place of drug administration, thrombosis, multiple pregnancies, skin allergic reactions.
Dosing and Administration
Syndrome of ovarian hyperstimulation (with the possible development of large ovarian cysts, ascites, hydrothorax, thromboembolism, oliguria, hypotension), multiple pregnancy, dyspeptic phenomena (nausea, vomiting), fever, arthralgia, mastalgia, gynecomastia (in men), skin rash, urticaria The formation of antibodies with prolonged use). Precautions Before the start of treatment it is necessary to exclude extragenital endocrinopathies. During the period of therapy, daily hormonal control and ultrasound of developing follicles are mandatory (the reaction of the ovaries can be evaluated according to the cervical index). If a syndrome of ovarian hyperstimulation threatens, menotropins are canceled. Do not mix with other medicines in the same syringe. In men with high blood levels of FSH, menotropins are ineffective. The prepared drug solution is used immediately.