Description
Pharmacodynamics
It alleviates or eliminates manifestations of climacteric syndrome (sensation of fever, sweating, dizziness, irritability, depressive state), prevents the development of osteoporosis, prevents the involution of the genital organs, normalizes the menstrual cycle in women of childbearing age, lowers testosterone levels in men.
Side effects
Headache, nausea, vomiting, weight gain, swelling, uterine bleeding, face skin pigmentation, erythema nodosum, transient elevation of transaminase levels in blood plasma, hyperbilirubinemia; Allergic reactions (rash); Rarely – hemorrhagic rashes on the skin, neoplasms of the endometrium.
Dosing and Administration
Inside. For cyclic use – 625 mcg – 1.25 mg per day, alternating between reception for 3 weeks with a break of 1 week, menstrual bleeding begins with the 5th day of the menstrual cycle, and from the 15th to the 21st day, an additional gestagenic Drug (with prolonged absence of menstruation, treatment is started any day).
If necessary, on the 5th-7th day of treatment, the daily dose can be increased to 3.75 mg, then it is reduced to 1.25 mg. Treatment of malignant neoplasms is 3.75-7.5 mg.
